Amikacin overdose in infant
نویسندگان
چکیده
منابع مشابه
Severe Apnea in a Premature Infant after Accidental Vancomycin Overdose Responsive to Treatment with Exchange Transfusion
Background: Mostly seen toxicities following vancomycin are ototoxicity and nephrotoxicity. We here report a very low birth weight preterm neonate who developed severe episodes of apnea after accidental iatrogenic vancomycin overdose, responsive to treatment with double volume exchange transfusion. Case report: A preterm neonate weighing 1380 grams received two doses of 10-fold of the normal do...
متن کاملAmikacin pharmacokinetics and suggested dosage modifications for the preterm infant.
The pharmacokinetics of amikacin administered intravenously at currently recommended doses (7.5 mg/kg every 12 h for infants with less than 7 days of life; 7.5 mg/kg every 8 h for infants with greater than 7 days of life) were studied in 28 preterm infants weighing less than 2,500 g (mean +/- standard deviation, 1.38 +/- 0.47 kg; postconceptional age, 30.50 +/- 2.86 weeks). The medication was i...
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Topical application of eye drops may cause mild or severe adverse ocular or systemic effects. Children, particularly infants, are more prone to systemic adverse effects of topical eye drops because of their lower body mass and blood volume, immature metabolism, and immaturity of excretory, nervous, and cardiovascular systems. Early recognition of signs and symptoms of systemic toxicity is very ...
متن کاملClinical Pharmacokinetics of Amikacin in Neonates
Amikacin is a bactericidal aminoglycoside. Aminoglycosides inhibit bacterial protein synthesis. The antibacterial spectrum of amikacin is the broadest of aminoglycosides. Because of its resistance to many of the aminoglycosides-inactivating enzymes, it has a special role in hospitals where gentamicin- and tobramycin-resistant microorganisms are prevalent. Amikacin is active against the majority...
متن کاملsevere apnea in a premature infant after accidental vancomycin overdose responsive to treatment with exchange transfusion
background: mostly seen toxicities following vancomycin are ototoxicity and nephrotoxicity. we here report a very low birth weight preterm neonate who developed severe episodes of apnea after accidental iatrogenic vancomycin overdose, responsive to treatment with double volume exchange transfusion. case report: a preterm neonate weighing 1380 grams received two doses of 10-fold of the normal do...
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ژورنال
عنوان ژورنال: IP International Journal of Medical Paediatrics and Oncology
سال: 2020
ISSN: 2581-4699,2581-4702
DOI: 10.18231/j.ijmpo.2020.031